My Dear Friends,
About 18 years ago, I decided to leave a successful career in IT to pursue a lifelong dream — to develop a set of technologies that would allow humans to age without losing and continuously improve. In my opinion, there is no cause more urgent, more altruistic, more impactful, more important, and more ambitious than enabling humans to improve continuously
. Aging is restricting our freedom in more ways than any regime, religion, or exploitive corporation. Aging is the major barrier to individual freedom, hope, and prosperity. It inhibits economic growth as well as our collective ability to develop sustainably and responsibly.
After 18 years in the longevity field, while there was significant progress made in many areas of science and technology, I realize that the progress is much slower than I originally expected. Although there are many emerging business models and substantial progress in enabling technologies, including those developed by the companies I run or advise, we are still far from curing or preventing Parkinson's or Alzheimer's, not talking about substantially slowing down or reversing aging.
What frustrates me is that most people do not pay enough attention to the inevitable decline, frailty, loss of function, diseases, and death that are associated with aging and choose to be distracted and spend their time on attention-grabbing causes that only provide a temporary reward. And many very talented human beings choose to focus on inventing, making, and selling stuff and content that people can easily live without instead of contributing to fighting the one silent enemy that is certain to kill everyone eventually. This may be because the problem feels so grand and unachievable that it is easier to rely on others to solve it sometime in the future. But the problem is here, right now, and every individual contributor can make a difference. Like climate change or poverty, aging research requires everyone on the planet to become involved
. But unlike climate change, aging is causing millions of casualties and suffering worldwide today and right now.
On the positive side, after two decades of hard work, my commercial ventures have started yielding financial returns. It would be logical to donate part of my wealth to charitable foundations focusing on aging research. However, my ventures are already focused on longevity or enabling technologies, and I do have a pretty good view of the recent trends. And I firmly believe that a company like Insilico Medicine will make much more impact in longevity biotechnology than any charity. That is why I continue to invest
in the company personally.
Over the past two decades, I supported many projects in longevity, saw many failures, analyzed a massive number of grants, and learned how to evaluate the impact of the various longevity initiatives. In addition to capital, I can now bring years of experience, and multiple partner organizations to the most impactful projects.
Therefore, I would like to pledge everything I have
now, and what I will get in the future, to only one cause — extending healthy productive longevity for all
human beings. Instead of donating just a portion of my wealth and energy to this cause, I would like to do more.
I pledge to spend 100% of my time and personal resources to accelerate research and clinical deployment of longevity technologies. At present, I am not married and do not have kids. I calculated that I can probably spend 6-7 hours a week on my personal life and I don't want to disappoint anyone by being a bad husband or a bad father. I will not marry until I meet someone as dedicated to the cause as I am. Also, if I ever reproduce, I pledge to train my kids to excel in biology, chemistry, computer science, and medicine and motivate them to prioritize extending healthy human longevity above all other values.
At present, I do not plan to leave an inheritance, and I will invest everything I have
into projects and companies that extend healthy, productive life for everyone on the planet.